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6FE7

Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-356

Summary for 6FE7
Entry DOI10.2210/pdb6fe7/pdb
Related6FDI 6FDS 6FDW 6FDX 6FE3
DescriptorcAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ... (9 entities in total)
Functional Keywordsphosphodiesterase, hydrolase, camp hydrolysis, alternative splicing
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight176331.95
Authors
Singh, A.K.,Brown, D.G. (deposition date: 2017-12-29, release date: 2019-04-10)
Primary citationSalado, I.G.,Moreno, C.,Sakaine, G.,Singh, A.K.,Blaazer, A.R.,Siderius, M.,Matheeussen, A.,Gul, S.,Maes, L.,Leurs, R.,Brown, D.G.,Augustyns, K.
hPDE4D2 structure with inhibitor NPD-356
To be published,
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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