6FDX
Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-1086
Summary for 6FDX
Entry DOI | 10.2210/pdb6fdx/pdb |
Related | 6FDI 6FDS 6FDW |
Descriptor | Phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 82963.74 |
Authors | |
Primary citation | Salado, I.G.,Moreno, C.,Sakaine, G.,Singh, A.K.,Blaazer, A.R.,Siderius, M.,Matheeussen, A.,Gul, S.,Maes, L.,Leurs, R.,Brown, D.G.,Augustyns, K. TbrPDEB1 structure with inhibitor NPD-1086 To be published, |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
Download full validation report