6EX9

Crystal Structure of HIV-1 Integrase Catalytic Core Domain with Inhibitor Peptide

Summary for 6EX9

DescriptorIntegrase, Inhibitor Peptide (3 entities in total)
Functional Keywordshiv-1, integrase, retroviruses, catalytic core, viral protein
Biological sourceHuman immunodeficiency virus 1
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Total number of polymer chains2
Total molecular weight18557.92
Authors
Galilee, M.,Alian, A. (deposition date: 2017-11-07, release date: 2018-06-06)
Primary citation
Galilee, M.,Alian, A.
Multimerization of HIV-1 integrase hinges on conserved SH3-docking platforms
Biorxiv, 2018
DOI: 10.1101/301721
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.014 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.282401.7%1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6ex9
no rotation
Molmil generated image of 6ex9
rotated about x axis by 90°
Molmil generated image of 6ex9
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 6ex9
no rotation
Molmil generated image of 6ex9
rotated about x axis by 90°
Molmil generated image of 6ex9
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6ex9.pdb1.gz [50.49 KB])