6EX9

Crystal Structure of HIV-1 Integrase Catalytic Core Domain with Inhibitor Peptide

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Functional Information from GO Data

ChainGOidnamespacecontents
A0042025cellular_componenthost cell nucleus
A0020002cellular_componenthost cell plasma membrane
A0072494cellular_componenthost multivesicular body
A0019013cellular_componentviral nucleocapsid
A0055036cellular_componentvirion membrane
A0004190molecular_functionaspartic-type endopeptidase activity
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0004533molecular_functionexoribonuclease H activity
A0042802molecular_functionidentical protein binding
A0008907molecular_functionintegrase activity
A0008289molecular_functionlipid binding
A0008233molecular_functionpeptidase activity
A0003723molecular_functionRNA binding
A0003964molecular_functionRNA-directed DNA polymerase activity
A0004523molecular_functionRNA-DNA hybrid ribonuclease activity
A0005198molecular_functionstructural molecule activity
A0008270molecular_functionzinc ion binding
A0006310biological_processDNA recombination
A0030260biological_processentry into host cell
A0075713biological_processestablishment of integrated proviral latency
A0019064biological_processfusion of virus membrane with host plasma membrane
A0039651biological_processinduction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
A0051169biological_processnuclear transport
A0006278biological_processRNA-dependent DNA biosynthetic process
A0039657biological_processsuppression by virus of host gene expression
A0019061biological_processuncoating of virus
A0044826biological_processviral genome integration into host DNA
A0019072biological_processviral genome packaging
A0019058biological_processviral life cycle
A0075732biological_processviral penetration into host nucleus
A0019068biological_processvirion assembly
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Functional Information from PDB Data

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

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Functional Information from PROSITE/UniProt

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Functional Information from SwissProt/UniProt

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Catalytic Information from CSA

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