6EJ5

A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner

Summary for 6EJ5

Entry DOI	10.2210/pdb6ej5/pdb
Descriptor	Regulator of nonsense transcripts 1 (2 entities in total)
Functional Keywords	rna helicase, sf1 superfamily, nmd factor, rna binding protein
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: Q92900
Total number of polymer chains	1
Total formula weight	71545.10
Authors	Gowravaram, M.,Bonneau, F.,Maciej, V.D.,Chakrabarti, S. (deposition date: 2017-09-20, release date: 2018-01-24, Last modification date: 2024-01-17)
Primary citation	Gowravaram, M.,Bonneau, F.,Kanaan, J.,Maciej, V.D.,Fiorini, F.,Raj, S.,Croquette, V.,Le Hir, H.,Chakrabarti, S. A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner. Nucleic Acids Res., 46:2648-2659, 2018 Cited by PubMed: 29378013 DOI: 10.1093/nar/gky040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.34 Å)

Structure validation