6EJ5

A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0016787	molecular_function	hydrolase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17159905","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17159905","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17159905","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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