6EJ5
A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Regulator of nonsense transcripts 1 | polymer | 637 | 71545.1 | 1 | UniProt (Q92900) Pfam (PF18141) Pfam (PF13086) Pfam (PF13087) | Homo sapiens (Human) | ATP-dependent helicase RENT1,Nonsense mRNA reducing factor 1,NORF1,Up-frameshift suppressor 1 homolog,hUpf1 |
| 2 | B (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 295 - 925 (UniProt: Q92900)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 71545.1 | |
| All* | Total formula weight | 71545.1 |
