6D8C
Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin
Summary for 6D8C
Entry DOI | 10.2210/pdb6d8c/pdb |
EMDB information | 7831 7832 7833 |
Related PRD ID | PRD_002307 |
Descriptor | Filamin-A, Actin, alpha skeletal muscle, Phalloidin, ... (5 entities in total) |
Functional Keywords | actin-binding domain, actin crosslinker, structural protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 13 |
Total formula weight | 386378.54 |
Authors | Iwamoto, D.V.,Huehn, A.R.,Simon, B.,Huet-Calderwood, C.,Baldassarre, M.,Sindelar, C.V.,Calderwood, D.A. (deposition date: 2018-04-26, release date: 2018-09-19, Last modification date: 2023-11-15) |
Primary citation | Iwamoto, D.V.,Huehn, A.,Simon, B.,Huet-Calderwood, C.,Baldassarre, M.,Sindelar, C.V.,Calderwood, D.A. Structural basis of the filamin A actin-binding domain interaction with F-actin. Nat. Struct. Mol. Biol., 25:918-927, 2018 Cited by PubMed: 30224736DOI: 10.1038/s41594-018-0128-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.54 Å) |
Structure validation
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