6B0U

Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a Lys-containing peptide

Summary for 6B0U

• Entry DOI: 10.2210/pdb6b0u/pdb
• Descriptor: N-acetyltransferase Eis, Synthetic peptide ATKAPAKKA, COENZYME A (3 entities in total)
• Functional Keywords: histone acetylation, aminoglycoside, drug resistance, tuberculosis, acetylation, transferase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 5
• Total formula weight: 145692.54

Authors

Biswas, T.,Pang, A.H.,Garneau-Tsodikova, S.,Tsodikov, O.V. (deposition date: 2017-09-15, release date: 2018-01-31, Last modification date: 2023-10-04)

• Primary citation: Green, K.D.,Biswas, T.,Pang, A.H.,Willby, M.J.,Reed, M.S.,Stuchlik, O.,Pohl, J.,Posey, J.E.,Tsodikov, O.V.,Garneau-Tsodikova, S.; Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight.; Biochemistry, 57:781-790, 2018; PubMed: 29345920; DOI: 10.1021/acs.biochem.7b01089

Experimental method

X-RAY DIFFRACTION (2.8 Å)