6B0U

Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a Lys-containing peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	N-acetyltransferase Eis	polymer	428	46692.9	3	UniProt (P9WFK7) Pfam (PF13527) Pfam (PF17668) Pfam (PF13530)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Aminoglycoside N-acetyltransferase,Enhanced intracellular survival protein,Protein-lysine N-acetyltransferase
2	D, E (D, E)	Synthetic peptide ATKAPAKKA	polymer	9	888.1	2		Mycobacterium tuberculosis H37Rv
3	F, G, H, I, J (A, B, C)	COENZYME A	non-polymer		767.5	5	Chemie (COA)

Sequence modifications

A, B, C: 1 - 402 (UniProt: P9WFK7)

PDB	External Database	Details
Met -25	-	initiating methionine
Gly -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Leu -12	-	expression tag
Val -11	-	expression tag
Pro -10	-	expression tag
Arg -9	-	expression tag
Gly -8	-	expression tag
Ser -7	-	expression tag
His -6	-	expression tag
Met -5	-	expression tag
Leu -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asp -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	141854.9
Non-Polymers*	Number of molecules	5
	Total formula weight	3837.7
All*	Total formula weight	145692.5

*Water molecules are not included.