6HBY
HLA class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope
Summary for 6HBY
Entry DOI | 10.2210/pdb6hby/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, ARRPPLAELAALNLSGSRL 5T4 tumour epitope, ... (7 entities in total) |
Functional Keywords | hla class ii, mhc ii, human, 5t4 tumor epitope, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 92166.05 |
Authors | MacLachlan, B.,Rizkallah, P.J.,Sewell, A.K.,Cole, D.K.,Godkin, A.J. (deposition date: 2018-08-13, release date: 2019-08-14, Last modification date: 2020-01-29) |
Primary citation | MacLachlan, B.J.,Dolton, G.,Papakyriakou, A.,Greenshields-Watson, A.,Mason, G.H.,Schauenburg, A.,Besneux, M.,Szomolay, B.,Elliott, T.,Sewell, A.K.,Gallimore, A.,Rizkallah, P.,Cole, D.K.,Godkin, A. Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. J.Biol.Chem., 294:20246-20258, 2019 Cited by PubMed: 31619516DOI: 10.1074/jbc.RA119.009437 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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