6BPI
Crystal structure of SETDB1 Tudor domain with aryl triazole fragment peptide conjugates
Summary for 6BPI
Entry DOI | 10.2210/pdb6bpi/pdb |
Related | 6AU2 6AU3 |
Descriptor | Histone-lysine N-methyltransferase SETDB1, MLY-SER-THR-E2G, SULFATE ION, ... (6 entities in total) |
Functional Keywords | setdb1 tudor, fragment hits, epigenetics, methyl lysine reader, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: Q15047 |
Total number of polymer chains | 2 |
Total formula weight | 26134.98 |
Authors | MADER, P.,Mendoza-Sanchez, R.,DONG, A.,DOBROVETSKY, E.,IQBAL, A.,CORLESS, V.,TEMPEL, W.,LIEW, S.K.,SMIL, D.,DELA SENA, C.C.,KENNEDY, S.,DIAZ, D.B.,SCHAPIRA, M.,VEDADI, M.,BROWN, P.J.,Santhakumar, V.,FRYE, S.,Bountra, C.,Edwards, A.M.,YUDIN, A.K.,Arrowsmith, C.H.,Structural Genomics Consortium (SGC) (deposition date: 2017-11-23, release date: 2017-12-27) |
Primary citation | MADER, P.,Mendoza-Sanchez, R.,DONG, A.,DOBROVETSKY, E.,IQBAL, A.,CORLESS, V.,TEMPEL, W.,LIEW, S.K.,SMIL, D.,DELA SENA, C.C.,KENNEDY, S.,DIAZ, D.B.,SCHAPIRA, M.,VEDADI, M.,BROWN, P.J.,Santhakumar, V.,FRYE, S.,Bountra, C.,Edwards, A.M.,YUDIN, A.K.,Arrowsmith, C.H.,Structural Genomics Consortium (SGC) Crystal structure of SETDB1 Tudor domain with aryl triazole fragment peptide conjugates to be published, |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
Download full validation report