6BPI
Crystal structure of SETDB1 Tudor domain with aryl triazole fragment peptide conjugates
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone-lysine N-methyltransferase SETDB1 | polymer | 213 | 24887.8 | 1 | UniProt (Q15047) Pfam (PF18300) Pfam (PF18359) Pfam (PF18358) In PDB | Homo sapiens (Human) | ERG-associated protein with SET domain,ESET,Histone H3-K9 methyltransferase 4,H3-K9-HMTase 4,Lysine N-methyltransferase 1E,SET domain bifurcated 1 |
| 2 | B | MLY-SER-THR-E2G | polymer | 4 | 676.8 | 1 | Homo sapiens | ||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | A | UNKNOWN ATOM OR ION | non-polymer | 3 | Chemie (UNX) | ||||
| 6 | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A: 196 - 402 (UniProt: Q15047)
| PDB | External Database | Details |
|---|---|---|
| Glu 190 | - | expression tag |
| Asn 191 | - | expression tag |
| Leu 192 | - | expression tag |
| Tyr 193 | - | expression tag |
| Phe 194 | - | expression tag |
| Gln 195 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25564.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 26135.0 |
