5ZLN

Crystal structure of mouse TLR9 in complex with two DNAs (CpG DNA and TCGCCA DNA)

Summary for 5ZLN

• Entry DOI: 10.2210/pdb5zln/pdb
• Descriptor: Toll-like receptor 9, DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*CP*GP*C)-3'), ... (8 entities in total)
• Functional Keywords: innate immunity, toll-like receptor, leucine-rich repeat, dna binding, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 6
• Total formula weight: 193496.96

Authors

Ishida, H.,Ohto, U.,Shimizu, T. (deposition date: 2018-03-28, release date: 2018-04-25, Last modification date: 2023-11-22)

• Primary citation: Ishida, H.,Ohto, U.,Shibata, T.,Miyake, K.,Shimizu, T.; Structural basis for species-specific activation of mouse Toll-like receptor 9; FEBS Lett., 592:2636-2646, 2018; PubMed: 29961984; DOI: 10.1002/1873-3468.13176

Experimental method

X-RAY DIFFRACTION (2.3 Å)