Crystal structure of paFAN1 bound to 1nt 5'flap DNA with gap

Summary for 5Y7G

DescriptorFanconi-associated nuclease 1 homolog, DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), DNA (5'-D(P*GP*AP*AP*TP*GP*TP*GP*TP*GP*TP*CP*TP*CP*AP*AP*TP*CP*CP*CP*AP*AP*CP*TP*T)-3'), ... (5 entities in total)
Functional Keywordsnuclease, hydrolase-dna complex, hydrolase/dna
Biological sourcePseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Total number of polymer chains12
Total molecular weight244990.94
Cho, Y.,Jin, H. (deposition date: 2017-08-17, release date: 2018-03-14, Last modification date: 2018-05-09)
Primary citation
Jin, H.,Roy, U.,Lee, G.,Scharer, O.D.,Cho, Y.
Structural mechanism of DNA interstrand cross-link unhooking by the bacterial FAN1 nuclease.
J. Biol. Chem., 293:6482-6496, 2018
PubMed: 29514982 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.RA118.002171
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.280170.3%6.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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