5Y7G

Crystal structure of paFAN1 bound to 1nt 5'flap DNA with gap

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003676	molecular_function	nucleic acid binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0004528	molecular_function	phosphodiesterase I activity
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0008409	molecular_function	5'-3' exonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0017108	molecular_function	5'-flap endonuclease activity
A	0030145	molecular_function	manganese ion binding
A	0036297	biological_process	interstrand cross-link repair
A	0046872	molecular_function	metal ion binding
A	0070336	molecular_function	flap-structured DNA binding
B	0000287	molecular_function	magnesium ion binding
B	0003676	molecular_function	nucleic acid binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004527	molecular_function	exonuclease activity
B	0004528	molecular_function	phosphodiesterase I activity
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0008409	molecular_function	5'-3' exonuclease activity
B	0016787	molecular_function	hydrolase activity
B	0016788	molecular_function	hydrolase activity, acting on ester bonds
B	0017108	molecular_function	5'-flap endonuclease activity
B	0030145	molecular_function	manganese ion binding
B	0036297	biological_process	interstrand cross-link repair
B	0046872	molecular_function	metal ion binding
B	0070336	molecular_function	flap-structured DNA binding
C	0000287	molecular_function	magnesium ion binding
C	0003676	molecular_function	nucleic acid binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004527	molecular_function	exonuclease activity
C	0004528	molecular_function	phosphodiesterase I activity
C	0006281	biological_process	DNA repair
C	0006974	biological_process	DNA damage response
C	0008409	molecular_function	5'-3' exonuclease activity
C	0016787	molecular_function	hydrolase activity
C	0016788	molecular_function	hydrolase activity, acting on ester bonds
C	0017108	molecular_function	5'-flap endonuclease activity
C	0030145	molecular_function	manganese ion binding
C	0036297	biological_process	interstrand cross-link repair
C	0046872	molecular_function	metal ion binding
C	0070336	molecular_function	flap-structured DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CA A 601

Chain	Residue
A	GLU368
A	ASP507
A	GLU522
A	VAL523
J	DC6

---

site_id	AC2
Number of Residues	4
Details	binding site for residue CA A 602

Chain	Residue
A	GLU386
A	ASP507
J	DA5
J	DC6

---

site_id	AC3
Number of Residues	5
Details	binding site for residue CA B 601

Chain	Residue
B	GLU368
B	ASP507
B	GLU522
B	VAL523
L	DA5

---

site_id	AC4
Number of Residues	6
Details	binding site for residue CA B 602

Chain	Residue
B	GLU368
B	TYR384
B	GLU386
B	ASP507
L	DC4
L	DA5

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CA C 601

Chain	Residue
C	GLU368
C	ASP507
C	GLU522
C	VAL523
C	LYS524
N	DC6

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	224
Details	Domain: {"description":"VRR-NUC","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25319828","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4R89","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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