5WLB

KRas G12V, bound to GppNHp and miniprotein 225-15a/b

Summary for 5WLB

• Entry DOI: 10.2210/pdb5wlb/pdb
• Related: 5WHA
• Descriptor: GTPase KRas, 225-15 a, 225-15 b, ... (8 entities in total)
• Functional Keywords: ras binders, gtp binding protein, protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01116
• Total number of polymer chains: 6
• Total formula weight: 55315.50

Authors

Shim, S.Y.,McGee, J.H.,Lee, S.-J.,Verdine, G.L. (deposition date: 2017-07-26, release date: 2018-01-03, Last modification date: 2023-10-04)

• Primary citation: McGee, J.H.,Shim, S.Y.,Lee, S.J.,Swanson, P.K.,Jiang, S.Y.,Durney, M.A.,Verdine, G.L.; Exceptionally high-affinity Ras binders that remodel its effector domain.; J. Biol. Chem., 293:3265-3280, 2018; PubMed: 29282294; DOI: 10.1074/jbc.M117.816348

Experimental method

X-RAY DIFFRACTION (1.72 Å)