5W0U

Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with dCMP

Summary for 5W0U

• Entry DOI: 10.2210/pdb5w0u/pdb
• Related: 5W0R 5W0Z
• Descriptor: Maltose-binding periplasmic protein,Single-stranded DNA cytosine deaminase, DNA (5'-D(*GP*TP*TP*CP*AP*AP*GP*GP*CP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*TP*GP*AP*AP*C)-3'), ... (8 entities in total)
• Functional Keywords: class switch recombination, cytidine deaminase, hydrolase-dna complex, hydrolase/dna
• Biological source: Escherichia coli O157:H7; More
• Cellular location: Nucleus : Q9GZX7
• Total number of polymer chains: 4
• Total formula weight: 131563.02

Authors

Qiao, Q.,Wang, L.,Wu, H. (deposition date: 2017-05-31, release date: 2017-08-16, Last modification date: 2023-10-04)

• Primary citation: Qiao, Q.,Wang, L.,Meng, F.L.,Hwang, J.K.,Alt, F.W.,Wu, H.; AID Recognizes Structured DNA for Class Switch Recombination.; Mol. Cell, 67:361-373.e4, 2017; PubMed: 28757211; DOI: 10.1016/j.molcel.2017.06.034

Experimental method

X-RAY DIFFRACTION (2.9 Å)