5VK2

Structural basis for antibody-mediated neutralization of Lassa virus

5VK2 の概要

• エントリーDOI: 10.2210/pdb5vk2/pdb
• 分子名称: Pre-glycoprotein polyprotein GP complex, Fab 37.7H heavy chain, Fab 37.7H light chain, ... (9 entities in total)
• 機能のキーワード: lassa, glycoprotein, arenavirus, antibody, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Lassa virus (LASV); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 299802.02

構造登録者

Hastie, K.M.,Zandonatti, M.A.,Kleinfelter, L.M.,Rowland, M.L.,Rowland, M.M.,Chandra, K.,Branco, L.M.,Robinson, J.E.,Garry, R.F.,Saphire, E.O. (登録日: 2017-04-20, 公開日: 2017-05-31, 最終更新日: 2023-10-04)

• 主引用文献: Hastie, K.M.,Zandonatti, M.A.,Kleinfelter, L.M.,Heinrich, M.L.,Rowland, M.M.,Chandran, K.,Branco, L.M.,Robinson, J.E.,Garry, R.F.,Saphire, E.O.; Structural basis for antibody-mediated neutralization of Lassa virus.; Science, 356:923-928, 2017; PubMed: 28572385; DOI: 10.1126/science.aam7260

実験手法

X-RAY DIFFRACTION (3.201 Å)