5UPU

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the presence of TBK6

5UPU の概要

• エントリーDOI: 10.2210/pdb5upu/pdb
• 関連するPDBエントリー: 4ZQM 4ZQN 4ZQO 4ZQP 4ZQR 5upv
• 分子名称: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, ~{N}-(2~{H}-indazol-6-yl)-3,5-dimethyl-1~{H}-pyrazole-4-sulfonamide, ... (4 entities in total)
• 機能のキーワード: impdh, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42282.16

構造登録者

Kim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Mulligan, R.,Gu, M.,Sacchettini, J.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2017-02-04, 公開日: 2017-02-22, 最終更新日: 2023-10-04)

• 主引用文献: Kim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Mulligan, R.,Gu, M.,Sacchettini, J.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the presence of TBK6; To Be Published,

実験手法

X-RAY DIFFRACTION (2.905 Å)