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5U8R

Structure of the ectodomain of the human Type 1 insulin-like growth factor receptor

Summary for 5U8R
Entry DOI10.2210/pdb5u8r/pdb
Related5U8Q
DescriptorInsulin-like growth factor 1 receptor, Fv 24-60 heavy chain, Fv 24-60 light chain, ... (8 entities in total)
Functional Keywordsreceptor, tyrosine kinase, type 1 insulin-like, growth factor receptor, transferase-immune system complex, transferase/immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight128934.84
Authors
Lawrence, M.,Xu, Y. (deposition date: 2016-12-14, release date: 2018-02-28, Last modification date: 2023-10-04)
Primary citationXu, Y.,Kong, G.K.,Menting, J.G.,Margetts, M.B.,Delaine, C.A.,Jenkin, L.M.,Kiselyov, V.V.,De Meyts, P.,Forbes, B.E.,Lawrence, M.C.
How ligand binds to the type 1 insulin-like growth factor receptor.
Nat Commun, 9:821-821, 2018
Cited by
PubMed: 29483580
DOI: 10.1038/s41467-018-03219-7
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.00001618041 Å)
Structure validation

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