5U8Q
Structure of the ectodomain of the human Type 1 insulin-like growth factor receptor in complex with IGF-I
Summary for 5U8Q
Entry DOI | 10.2210/pdb5u8q/pdb |
Related | 5U8R |
Descriptor | Insulin-like growth factor 1 receptor, Insulin-like growth factor I, Fv 24-60 heavy chain, ... (9 entities in total) |
Functional Keywords | receptor tyrosine kinase, type 1 insulin-like growth factor receptor, insulin-like growth-factor i, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 137018.95 |
Authors | Lawrence, M.,Xu, Y. (deposition date: 2016-12-14, release date: 2018-02-28, Last modification date: 2023-10-04) |
Primary citation | Xu, Y.,Kong, G.K.,Menting, J.G.,Margetts, M.B.,Delaine, C.A.,Jenkin, L.M.,Kiselyov, V.V.,De Meyts, P.,Forbes, B.E.,Lawrence, M.C. How ligand binds to the type 1 insulin-like growth factor receptor. Nat Commun, 9:821-821, 2018 Cited by PubMed: 29483580DOI: 10.1038/s41467-018-03219-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.27104018461 Å) |
Structure validation
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