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5U8Q

Structure of the ectodomain of the human Type 1 insulin-like growth factor receptor in complex with IGF-I

Functional Information from GO Data
ChainGOidnamespacecontents
B0005179molecular_functionhormone activity
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0008083molecular_functiongrowth factor activity
Functional Information from PROSITE/UniProt
site_idPS00262
Number of Residues15
DetailsINSULIN Insulin family signature. CCFRsCDlrrLemyC
ChainResidueDetails
BCYS47-CYS61

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues194
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:9690478
ChainResidueDetails
AASN21
AASN105
AASN214
AASN284

site_idSWS_FT_FI3
Number of Residues12
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN72
AASN754
AVAL890
APHE903
AASN387
AASN408
AASN504
AASN577
AASN592
AASN610
AASN737
APRO746

226707

PDB entries from 2024-10-30

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