5U52

2 helix minimized version of the B-domain from Protein A (Z34C0 bound to IgG1 Fc (monoclinic form)

Summary for 5U52

Entry DOI	10.2210/pdb5u52/pdb
Related	1L6X 5U4Y 5U66
Descriptor	IGG1 FC, Mini Z domain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	2 helix bundle, protein a, b-domain, igg1 fc, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	58613.48
Authors	Ultsch, M.H.,Eigenbrot, C. (deposition date: 2016-12-06, release date: 2017-05-24, Last modification date: 2023-10-04)
Primary citation	Ultsch, M.,Braisted, A.,Maun, H.R.,Eigenbrot, C. 3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix. Protein Eng. Des. Sel., 30:619-625, 2017 Cited by PubMed: 28475752 DOI: 10.1093/protein/gzx029 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.942 Å)

Structure validation