5U66

Modified single helix from the B-domain of protein A bound to IgG1 Fc

Summary for 5U66

• Entry DOI: 10.2210/pdb5u66/pdb
• Related PRD ID: PRD_002261
• Descriptor: STAPLED PEPTIDE FROM DOMAIN B OF PROTEIN A, IgG1 fc derived from CD4-fc fusion, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: igg1 fc, staple peptide, protein a, b-domain, immune system-inhibitor complex, immune system/inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 26896.14

Authors

Ultsch, M.H.,Eigenbrot, C. (deposition date: 2016-12-07, release date: 2017-05-24, Last modification date: 2023-11-15)

• Primary citation: Ultsch, M.,Braisted, A.,Maun, H.R.,Eigenbrot, C.; 3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix.; Protein Eng. Des. Sel., 30:619-625, 2017; PubMed: 28475752; DOI: 10.1093/protein/gzx029

Experimental method

X-RAY DIFFRACTION (1.7 Å)