5U33
Crystal structure of AacC2c1-sgRNA-extended non-target DNA ternary complex
Summary for 5U33
Entry DOI | 10.2210/pdb5u33/pdb |
Related | 5U30 5U31 5U34 |
Descriptor | CRISPR-associated endonuclease C2c1, sgRNA, Target DNA strand, ... (5 entities in total) |
Functional Keywords | type v crispr-cas endonculease: c2c1: structure: binary complex with sgrna: ternary complex with added dna: ruvc catalytic pocket: sequence-specific pam recognition: genome editing tool, hydrolase-dna complex, hydrolase/dna |
Biological source | Alicyclobacillus acidoterrestris (strain ATCC 49025 / DSM 3922 / CIP 106132 / NCIMB 13137 / GD3B) More |
Total number of polymer chains | 4 |
Total formula weight | 184106.79 |
Authors | Yang, H.,Gao, P.,Rajashankar, K.R.,Patel, D.J. (deposition date: 2016-12-01, release date: 2017-01-25, Last modification date: 2023-10-04) |
Primary citation | Yang, H.,Gao, P.,Rajashankar, K.R.,Patel, D.J. PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease. Cell, 167:1814-1828.e12, 2016 Cited by PubMed: 27984729DOI: 10.1016/j.cell.2016.11.053 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.75 Å) |
Structure validation
Download full validation report