5TZT

Crystal structure of human CD47 ECD bound to Fab of C47B161

Summary for 5TZT

• Entry DOI: 10.2210/pdb5tzt/pdb
• Related: 5TZ2 5TZU
• Descriptor: Light Chain of Fab C47B161, Heavy Chain of Fab C47B161, Leukocyte surface antigen CD47, ... (6 entities in total)
• Functional Keywords: antigen-fab complex, immunoglobulin, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 127523.48

Authors

Cardoso, R.M.F. (deposition date: 2016-11-22, release date: 2017-03-15, Last modification date: 2023-10-04)

• Primary citation: Pietsch, E.C.,Dong, J.,Cardoso, R.,Zhang, X.,Chin, D.,Hawkins, R.,Dinh, T.,Zhou, M.,Strake, B.,Feng, P.H.,Rocca, M.,Santos, C.D.,Shan, X.,Danet-Desnoyers, G.,Shi, F.,Kaiser, E.,Millar, H.J.,Fenton, S.,Swanson, R.,Nemeth, J.A.,Attar, R.M.; Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies.; Blood Cancer J, 7:e536-e536, 2017; PubMed: 28234345; DOI: 10.1038/bcj.2017.7

Experimental method

X-RAY DIFFRACTION (2.89 Å)