5ONC

Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch

5ONC の概要

• エントリーDOI: 10.2210/pdb5onc/pdb
• 関連するPDBエントリー: 4ubt 4ubu 4ubv 4ubw
• 分子名称: Steroid 3-ketoacyl-CoA thiolase, CHLORIDE ION (3 entities in total)
• 機能のキーワード: oxidative stress, cholesterol metabolism, lipid degradation, steroid metabolism, mycobacterium tuberculosis, biosynthetic protein
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 84870.71

構造登録者

Schaefer, C.,Kuper, J.,Sampson, N.S.,Kisker, C. (登録日: 2017-08-03, 公開日: 2017-08-23, 最終更新日: 2024-01-17)

• 主引用文献: Lu, R.,Schaefer, C.M.,Nesbitt, N.M.,Kuper, J.,Kisker, C.,Sampson, N.S.; Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis Is Controlled by a Redox-Sensitive Thiol Switch.; ACS Infect Dis, 3:666-675, 2017; PubMed: 28786661; DOI: 10.1021/acsinfecdis.7b00072

実験手法

X-RAY DIFFRACTION (2.19 Å)