5ONC

Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Steroid 3-ketoacyl-CoA thiolase	polymer	399	42346.7	2	UniProt (I6XHI4) Pfam (PF00108) Pfam (PF02803)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Acetyl-CoA acetyltransferase FadA5,Beta-ketoacyl-CoA thiolase
2	C, D, E, F, G (A, B)	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
3	H, I (A, B)	water	water		18.0	211	Chemie (HOH)

Sequence modifications

A, B: 1 - 391 (UniProt: I6XHI4)

PDB	External Database	Details
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84693.4
Non-Polymers*	Number of molecules	5
	Total formula weight	177.3
All*	Total formula weight	84870.7

*Water molecules are not included.