4UBV
Structure of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis with an partially acetylated cysteine in complex with acetyl-CoA and CoA
Summary for 4UBV
Entry DOI | 10.2210/pdb4ubv/pdb |
Descriptor | Acetyl-CoA acetyltransferase FadA5, ACETYL COENZYME *A, COENZYME A, ... (7 entities in total) |
Functional Keywords | partially acetylated degradative thiolase, acetyl-coa, coa, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 89048.14 |
Authors | Schaefer, C.M.,Kisker, C. (deposition date: 2014-08-13, release date: 2014-12-17, Last modification date: 2023-12-20) |
Primary citation | Schaefer, C.M.,Lu, R.,Nesbitt, N.M.,Schiebel, J.,Sampson, N.S.,Kisker, C. FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis. Structure, 23:21-33, 2015 Cited by PubMed: 25482540DOI: 10.1016/j.str.2014.10.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report