4UBV
Structure of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis with an partially acetylated cysteine in complex with acetyl-CoA and CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetyl-CoA acetyltransferase FadA5 | polymer | 399 | 42346.7 | 2 | UniProt (I6XHI4) Pfam (PF00108) Pfam (PF02803) | Mycobacterium tuberculosis | Probable acetyl-CoA acetyltransferase FadA5 (Acetoacetyl-CoA thiolase) |
| 2 | C (A) | ACETYL COENZYME *A | non-polymer | 809.6 | 1 | Chemie (ACO) | |||
| 3 | D, M (A, B) | COENZYME A | non-polymer | 767.5 | 2 | Chemie (COA) | |||
| 4 | E, F, N (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | G, H, O, P, Q... (A, B) | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 7 | Chemie (DIO) | |||
| 6 | AA, I, J, K, L... (B, A) | GLYCEROL | non-polymer | 92.1 | 12 | Chemie (GOL) | |||
| 7 | BA, CA (A, B) | water | water | 18.0 | 281 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 391 (UniProt: I6XHI4)
| PDB | External Database | Details |
|---|---|---|
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Cys 93 | Scy 101 | microheterogeneity/modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84693.4 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 4354.7 | |
| All* | Total formula weight | 89048.1 |
