4UBU

Structure of a modified C93S variant of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis in complex with CoA

Summary for 4UBU

Entry DOI	10.2210/pdb4ubu/pdb
Descriptor	Acetyl-CoA acetyltransferase FadA5, COENZYME A, GLYCEROL, ... (4 entities in total)
Functional Keywords	acetylated, degradative thiolase, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	8
Total formula weight	345490.21
Authors	Schaefer, C.M.,Kisker, C. (deposition date: 2014-08-13, release date: 2014-12-17, Last modification date: 2023-12-20)
Primary citation	Schaefer, C.M.,Lu, R.,Nesbitt, N.M.,Schiebel, J.,Sampson, N.S.,Kisker, C. FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis. Structure, 23:21-33, 2015 Cited by PubMed: 25482540 DOI: 10.1016/j.str.2014.10.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation