5NIE
Crystal structure of human LTA4H mutant R563A in open conformation
Summary for 5NIE
Entry DOI | 10.2210/pdb5nie/pdb |
Related | 4DPR 4MS6 5NI2 5NI4 5NI6 5NIA 5NID |
Descriptor | Leukotriene A-4 hydrolase, ZINC ION (3 entities in total) |
Functional Keywords | metallopeptidase, epoxide hydrolase, open conformation, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P09960 |
Total number of polymer chains | 3 |
Total formula weight | 210516.43 |
Authors | Stsiapanava, A. (deposition date: 2017-03-23, release date: 2017-08-23, Last modification date: 2024-01-17) |
Primary citation | Stsiapanava, A.,Samuelsson, B.,Haeggstrom, J.Z. Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis. Proc. Natl. Acad. Sci. U.S.A., 114:9689-9694, 2017 Cited by PubMed: 28827365DOI: 10.1073/pnas.1710850114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.603 Å) |
Structure validation
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