5NG9

Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with agonist CIP-AS at 1.15 A resolution.

Summary for 5NG9

Entry DOI	10.2210/pdb5ng9/pdb
Descriptor	Glutamate receptor 2, CITRATE ANION, LITHIUM ION, ... (8 entities in total)
Functional Keywords	ionotropic glutamate receptor, ampa receptor, ligand-binding domain, glua2, glur2, agonist, membrane protein
Biological source	Rattus norvegicus (Norway Rat) More
Cellular location	Cell membrane; Multi-pass membrane protein: P19491
Total number of polymer chains	1
Total formula weight	30447.45
Authors	Laulumaa, S.,Frydenvang, K.A.,Winther, S.,Kastrup, J.S. (deposition date: 2017-03-17, release date: 2017-07-26, Last modification date: 2024-01-17)
Primary citation	Mllerud, S.,Pinto, A.,Marconi, L.,Frydenvang, K.,Thorsen, T.S.,Laulumaa, S.,Venskutonyte, R.,Winther, S.,Moral, A.M.C.,Tamborini, L.,Conti, P.,Pickering, D.S.,Kastrup, J.S. Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors. ACS Chem Neurosci, 8:2056-2064, 2017 Cited by PubMed: 28691798 DOI: 10.1021/acschemneuro.7b00201 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.15 Å)

Structure validation