5NG9
Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with agonist CIP-AS at 1.15 A resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glutamate receptor 2 | polymer | 264 | 29278.7 | 1 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB | Rattus norvegicus (Norway Rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | A | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
| 3 | A | LITHIUM ION | non-polymer | 6.9 | 1 | Chemie (LI) | |||
| 4 | A | (3~{a}~{S},4~{S},6~{a}~{R})-4,5,6,6~{a}-tetrahydro-3~{a}~{H}-pyrrolo[3,4-d][1,2]oxazole-3,4-dicarboxylic acid | non-polymer | 200.1 | 1 | Chemie (8VN) | |||
| 5 | A | (2~{S},3~{R},4~{R})-3-(carboxycarbonyl)-4-oxidanyl-pyrrolidine-2-carboxylic acid | non-polymer | 203.1 | 1 | Chemie (8WQ) | |||
| 6 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | water | water | 18.0 | 437 | Chemie (HOH) |
Sequence modifications
A: 3 - 117 (UniProt: P19491)
A: 120 - 264 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ala 2 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29278.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1168.7 | |
| All* | Total formula weight | 30447.5 |
