5MHA

D-2-hydroxyacid dehydrogenases (D2-HDH) from Haloferax mediterranei in complex with a mixture of 2-ketohexanoic acid and 2-hydroxyhexanoic acid, and NADPH (1.57 A resolution)

5MHA の概要

• エントリーDOI: 10.2210/pdb5mha/pdb
• 関連するPDBエントリー: 5MH5 5MH6
• 分子名称: D-2-hydroxyacid dehydrogenase, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (8 entities in total)
• 機能のキーワード: d-2-hydroxyacid dehydrogenase, halophile, chiral specificity, reaction mechanism, oxidoreductase
• 由来する生物種: Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69382.01

構造登録者

Bisson, C.,Baker, P.J.,Domenech Perez, J.,Pramanpol, N.,Harding, S.E.,Rice, D.W.,Ferrer, J. (登録日: 2016-11-23, 公開日: 2018-05-09, 最終更新日: 2022-12-28)

• 主引用文献: Domenech Perez, J.,Pramanpol, N.,Baker, P.J.,Bisson, C.,Harding, S.E.,Rice, D.W.,Ferrer, J.; Productive ternary complexes of D-2-hydroxyacid dehydrogenase provide insights into the chiral specificity of its reaction mechanism; To Be Published,

実験手法

X-RAY DIFFRACTION (1.57 Å)