5LX5

CRYSTAL STRUCTURE OF VISFATIN IN COMPLEX WITH SAR154782-RP.

Summary for 5LX5

• Entry DOI: 10.2210/pdb5lx5/pdb
• Descriptor: Nicotinamide phosphoribosyltransferase, [(2~{R},3~{S},4~{R},5~{R})-5-[2-azanyl-5-[[[4-[6-(ethylamino)-5-(2-piperidin-1-ylethylcarbamoyl)pyridin-2-yl]-2-fluoranyl-phenyl]carbamoylamino]methyl]pyridin-1-ium-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: transferase, nampt, inhibitor, drug design, cancer
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P43490
• Total number of polymer chains: 2
• Total formula weight: 113289.49

Authors

Bertrand, T.,Marquette, J.P. (deposition date: 2016-09-20, release date: 2017-10-25)

• Primary citation: Bertrand, T.,Marquette, J.P.; CRYSTAL STRUCTURE OF VISFATIN IN COMPLEX WITH SAR154782-RP; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.88 Å)