5LX5
CRYSTAL STRUCTURE OF VISFATIN IN COMPLEX WITH SAR154782-RP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nicotinamide phosphoribosyltransferase | polymer | 493 | 55723.1 | 2 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) | Homo sapiens (Human) | Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin |
| 2 | C, E (A, B) | [(2~{R},3~{S},4~{R},5~{R})-5-[2-azanyl-5-[[[4-[6-(ethylamino)-5-(2-piperidin-1-ylethylcarbamoyl)pyridin-2-yl]-2-fluoranyl-phenyl]carbamoylamino]methyl]pyridin-1-ium-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate | non-polymer | 747.7 | 2 | Chemie (7A0) | |||
| 3 | D, F (A, B) | DIPHOSPHATE | non-polymer | 173.9 | 2 | Chemie (DPO) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 940 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 491 (UniProt: P43490)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 111446.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1843.3 | |
| All* | Total formula weight | 113289.5 |
