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5LX5

CRYSTAL STRUCTURE OF VISFATIN IN COMPLEX WITH SAR154782-RP.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BNicotinamide phosphoribosyltransferasepolymer49355723.12UniProt (P43490)
Pfam (PF18127)
Pfam (PF04095)
In PDB
Homo sapiens (Human)Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin
2A, B[(2~{R},3~{S},4~{R},5~{R})-5-[2-azanyl-5-[[[4-[6-(ethylamino)-5-(2-piperidin-1-ylethylcarbamoyl)pyridin-2-yl]-2-fluoranyl-phenyl]carbamoylamino]methyl]pyridin-1-ium-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphatenon-polymer747.72Chemie (7A0)
3A, BDIPHOSPHATEnon-polymer173.92Chemie (DPO)
4waterwater18.0940Chemie (HOH)
Sequence modifications
A, B: 1 - 491 (UniProt: P43490)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight111446.1
Non-Polymers*Number of molecules4
Total formula weight1843.3
All*Total formula weight113289.5
*Water molecules are not included.

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PDB entries from 2024-05-01

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