5LUZ

Structure of Human Neurolysin (E475Q) in complex with neurotensin peptide products

Summary for 5LUZ

Entry DOI	10.2210/pdb5luz/pdb
Descriptor	Neurolysin, mitochondrial, PRO-ARG-ARG-PRO neurotensin fragment, ZINC ION, ... (6 entities in total)
Functional Keywords	protease, mitochondria, hydrolase, neurotensin
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	164287.17
Authors	Masuyer, G.,Berntsson, R.P.-A.,Teixeira, P.F.,Kmiec, B.,Glaser, E.,Stenmark, P. (deposition date: 2016-09-12, release date: 2017-12-06, Last modification date: 2024-01-17)
Primary citation	Teixeira, P.F.,Masuyer, G.,Pinho, C.M.,Branca, R.M.M.,Kmiec, B.,Wallin, C.,Warmlander, S.K.T.S.,Berntsson, R.P.,Ankarcrona, M.,Graslund, A.,Lehtio, J.,Stenmark, P.,Glaser, E. Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin. J. Mol. Biol., 430:348-362, 2018 Cited by PubMed: 29183787 DOI: 10.1016/j.jmb.2017.11.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation