5KM5
Human Histidine Triad Nucleotide Binding Protein 2 (hHint2) triciribine 5'-monoposphate catalytic product complex
Summary for 5KM5
Entry DOI | 10.2210/pdb5km5/pdb |
Related | 3TW2 5IPB 5IPC 5IPD 5IPE 5KLY 5KLZ 5KM0 5KM1 5KM2 5KM3 5KM4 5KM6 5KM7 5KM8 5KM9 5KMA 5KMB 5KMC |
Descriptor | Histidine triad nucleotide-binding protein 2, mitochondrial, CHLORIDE ION, TETRAETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | hint, histidine triad, hit, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Mitochondrion : Q9BX68 |
Total number of polymer chains | 2 |
Total formula weight | 31072.62 |
Authors | Maize, K.M.,Finzel, B.C. (deposition date: 2016-06-26, release date: 2017-06-28, Last modification date: 2023-09-27) |
Primary citation | Maize, K.M.,Shah, R.,Strom, A.,Kumarapperuma, S.,Zhou, A.,Wagner, C.R.,Finzel, B.C. A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides. Mol. Pharm., 14:3987-3997, 2017 Cited by PubMed: 28968488DOI: 10.1021/acs.molpharmaceut.7b00664 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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