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5KM5

Human Histidine Triad Nucleotide Binding Protein 2 (hHint2) triciribine 5'-monoposphate catalytic product complex

Summary for 5KM5
Entry DOI10.2210/pdb5km5/pdb
Related3TW2 5IPB 5IPC 5IPD 5IPE 5KLY 5KLZ 5KM0 5KM1 5KM2 5KM3 5KM4 5KM6 5KM7 5KM8 5KM9 5KMA 5KMB 5KMC
DescriptorHistidine triad nucleotide-binding protein 2, mitochondrial, CHLORIDE ION, TETRAETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywordshint, histidine triad, hit, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationMitochondrion : Q9BX68
Total number of polymer chains2
Total formula weight31072.62
Authors
Maize, K.M.,Finzel, B.C. (deposition date: 2016-06-26, release date: 2017-06-28, Last modification date: 2023-09-27)
Primary citationMaize, K.M.,Shah, R.,Strom, A.,Kumarapperuma, S.,Zhou, A.,Wagner, C.R.,Finzel, B.C.
A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides.
Mol. Pharm., 14:3987-3997, 2017
Cited by
PubMed: 28968488
DOI: 10.1021/acs.molpharmaceut.7b00664
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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