5KCO

SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy

Summary for 5KCO

• Entry DOI: 10.2210/pdb5kco/pdb
• Related: 5KCH
• Descriptor: Histone-lysine N-methyltransferase SETDB1, SULFATE ION, ~{N}-(4-chlorophenyl)methanesulfonamide, ... (6 entities in total)
• Functional Keywords: fragment screening, diamond i04-1 xchem, pandda, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus: Q15047
• Total number of polymer chains: 1
• Total formula weight: 31484.50

Authors

Tempel, W.,Harding, R.J.,Mader, P.,Dobrovetsky, E.,Walker, J.R.,Brown, P.J.,Schapira, M.,Collins, P.,Pearce, N.,Brandao-Neto, J.,Douangamath, A.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Santhakumar, V.,Structural Genomics Consortium (SGC) (deposition date: 2016-06-06, release date: 2016-07-27, Last modification date: 2023-09-27)

• Primary citation: Tempel, W.,Harding, R.J.,Mader, P.,Dobrovetsky, E.,Walker, J.R.,Brown, P.J.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Santhakumar, S.,Structural Genomics Consortium (SGC); SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.47 Å)