5KCH

SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy into weak electron density

Summary for 5KCH

• Entry DOI: 10.2210/pdb5kch/pdb
• Related: 5KCO
• Descriptor: Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION, DIMETHYL SULFOXIDE, ... (6 entities in total)
• Functional Keywords: fragment screening, diamond i04-1 xchem, pandda, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 42939.77

Authors

Tempel, W.,Harding, R.J.,Mader, P.,Dobrovetsky, E.,Walker, J.R.,Brown, P.J.,Schapira, M.,Collins, P.,Pearce, N.,Brandao-Neto, J.,Douangamath, A.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Santhakumar, V.,Structural Genomics Consortium (SGC) (deposition date: 2016-06-06, release date: 2016-07-27, Last modification date: 2023-09-27)

• Primary citation: Tempel, W.,Harding, R.J.,Mader, P.,Dobrovetsky, E.,Walker, J.R.,Brown, P.J.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Santhakumar, S.,Structural Genomics Consortium (SGC); SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)