5KCH

SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy into weak electron density

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue DMS A 551

Chain	Residue
A	LYS207
A	LYS211
A	HOH641

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site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 552

Chain	Residue
A	HIS214
A	LYS215
A	HOH608
A	HOH616
A	HOH619

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site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 553

Chain	Residue
A	TRP363
A	LYS364
A	ASP381
A	HOH611
A	ARG209

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site_id	AC4
Number of Residues	9
Details	binding site for residue 6RN A 554

Chain	Residue
A	PHE296
A	PHE297
A	GLY300
A	TYR301
A	SER328
A	CYS329
A	PHE332
A	SER392
A	HOH676

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	50
Details	Domain: {"description":"Tudor 1; degenerate","evidences":[{"source":"PubMed","id":"29234025","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	63
Details	Domain: {"description":"Tudor 2","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29234025","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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