5KCO
SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | HIS214 |
| A | LYS215 |
| A | HOH612 |
| A | HOH634 |
| A | HOH639 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | HOH614 |
| A | ARG209 |
| A | TRP363 |
| A | LYS364 |
| A | ASP381 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue 6RO A 503 |
| Chain | Residue |
| A | PHE296 |
| A | GLY300 |
| A | ALA302 |
| A | SER328 |
| A | PHE332 |
| A | TYR389 |
| A | SER392 |
| A | HOH655 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 551 |
| Chain | Residue |
| A | LYS207 |
| A | LYS208 |
| A | LYS211 |
| A | HOH652 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 552 |
| Chain | Residue |
| A | TRP358 |
| A | TRP363 |
| A | PHE379 |
| A | ASP382 |
| A | ARG384 |
| A | HOH609 |
| A | HOH672 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 553 |
| Chain | Residue |
| A | GLU190 |
| A | ASN191 |
| A | THR223 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 63 |
| Details | Domain: {"description":"Tudor 1"} |
| Chain | Residue | Details |
