5JHG
Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11
Summary for 5JHG
Entry DOI | 10.2210/pdb5jhg/pdb |
Related | 5JHH |
Descriptor | Rho guanine nucleotide exchange factor 11, Transforming protein RhoA, GLYCEROL, ... (4 entities in total) |
Functional Keywords | rhoa-arhrhogef11 complex, target-based pharmaceutical design, signaling protein-transcription complex, signaling protein/transcription |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : O15085 Cell membrane; Lipid-anchor; Cytoplasmic side: P61586 |
Total number of polymer chains | 4 |
Total formula weight | 127118.60 |
Authors | |
Primary citation | Wang, R.,Yan, Z.,Lv, Z.,Ma, L.,Wang, F.,Li, J.,Miao, L. Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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