5JHG
Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, E) | Rho guanine nucleotide exchange factor 11 | polymer | 369 | 42907.7 | 2 | UniProt (O15085) Pfam (PF00621) Pfam (PF17838) | Homo sapiens (Human) | PDZ-RhoGEF |
| 2 | B, D (B, F) | Transforming protein RhoA | polymer | 181 | 20467.5 | 2 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (Human) | Rho cDNA clone 12,h12 |
| 3 | E, F, G, H (A, B, E) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | I, J, K, L (A, B, E, F) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A, E: 714 - 1081 (UniProt: O15085)
| PDB | External Database | Details |
|---|---|---|
| Met 713 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 126750.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 368.4 | |
| All* | Total formula weight | 127118.6 |
