5I07

tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 6-Amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Summary for 5I07

• Entry DOI: 10.2210/pdb5i07/pdb
• Related: 1P0D 1Y5V 1Y5W 1Y5X 3EOS 3GE7 4FR6 4FSA 4KWO 4LEQ 4PUK 5I00 5I02 5I06
• Descriptor: Queuine tRNA-ribosyltransferase, GLYCEROL, ZINC ION, ... (6 entities in total)
• Functional Keywords: co-crystallization, shigellosis, transferase, transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
• Total number of polymer chains: 2
• Total formula weight: 87085.40

Authors

Ehrmann, F.R.,Nguyen, D.,Heine, A.,Klebe, G. (deposition date: 2016-02-03, release date: 2017-02-15, Last modification date: 2024-01-10)

• Primary citation: Ehrmann, F.R.,Stojko, J.,Heine, A.,Diederich, F.,Reiter, K.,Sanglier-Cianferani, S.,Klebe, G.; Co-crystallization, Isothermal titration calorimetry and nanoESI-MS reveal dimer disturbing inhibitors; To be Published,

Experimental method

X-RAY DIFFRACTION (1.89 Å)