5I07
tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 6-Amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Queuine tRNA-ribosyltransferase | polymer | 386 | 42925.7 | 2 | UniProt (P28720) Pfam (PF01702) | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) | Guanine insertion enzyme,tRNA-guanine transglycosylase |
| 2 | C, D, E, J (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 3 | F, K (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, L (A, B) | 6-AMINO-4-(2-PHENYLETHYL)-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE | non-polymer | 305.3 | 2 | Chemie (NE8) | |||
| 5 | H, I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 432 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 386 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Lys 312 | Thr 312 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85851.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1234.0 | |
| All* | Total formula weight | 87085.4 |
