5HY8

Glycation restrains allosteric transition in hemoglobin: The molecular basis of oxidative stress under hyperglycemic conditions in diabetes

Summary for 5HY8

• Entry DOI: 10.2210/pdb5hy8/pdb
• Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... (7 entities in total)
• Functional Keywords: glycation, hemoglobin, diabetes, oxidative stress, oxygen transport
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 162344.24

Authors

Saraswathi, N.T.,Pannu, N.S.,Syakhovich, V.E.,Saurabh, A.,Bokut, S.B.,Moras, D.,Ruff, M. (deposition date: 2016-02-01, release date: 2017-02-01, Last modification date: 2025-10-01)

• Primary citation: Saraswathi, N.T.,Pannu, N.S.,Syakhovich, V.E.,Saurabh, A.,Bokut, S.B.,Moras, D.,Ruff, M.; Glycation restrains allosteric transition in hemoglobin: The molecular basis of oxidative stress under hyperglycemic conditions in diabetes; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)